The Victory 112 Neo cabinet is recommended for anyone wanting to run V4 The Duchess guitar amp at its full 180 watts into 4-ohms.
The Neo 250 Copperback is a very powerful, efficient speaker that uses a neodymium magnet (instead of the more common and much heavier ceramic or alnico). As such it is a very transparent sounding speaker that does not have the cone break-up or midrange growl of a more traditional Celestion speaker. It's worth keeping this in mind when you set EQ and/or put a mic in front of it. Tremendous power and clarity is what you get.